SCHEMBL9828405

SCHEMBL9828405

Cc1ccc(C(c2ccc(C)c(C)c2)(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
TSHR P16473 1/20 0.39
MLYCD O95822 1/20 0.39
CA2 P00918 2/20 0.38
CA1 P00915 1/20 0.38
CA5A P35218 1/20 0.38
CA9 Q16790 1/20 0.38
KIF11 P52732 3/20 0.34
TDP1 Q9NUW8 3/20 0.33
ALDH1A1 P00352 2/20 0.33
ACHE P22303 2/20 0.33
CYP19A1 P11511 2/20 0.33
NFE2L2 Q16236 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NPC1 O15118 2/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
NPBWR1 P48145 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13538944 0.94 ESR1 (0.50) ESR1ESR2TSHRMLYCDKIF11
SCHEMBL47866 0.91 ESR1 (0.46) ESR1ESR2TSHRMLYCDKIF11
SCHEMBL29728144 0.91 ESR1 (0.46) ESR1ESR2TSHRMLYCDKIF11
SCHEMBL25919760 0.87 ESR1 (0.56) ESR1ESR2TSHRMLYCDCA2
SCHEMBL275315 0.87 ESR1 (0.56) ESR1ESR2TSHRMLYCDCA2
SCHEMBL10007145 0.86 CYP19A1 (0.45) ESR1ESR2TSHRKIF11ALDH1A1
SCHEMBL11947069 0.86 ESR1 (0.39) ESR1ESR2MLYCDKIF11ALDH1A1
SCHEMBL13538943 0.83 ESR1 (0.40) ESR1ESR2TSHRKIF11ALDH1A1
SCHEMBL12792076 0.82 ACHE (0.39) ESR1ESR2KIF11ALDH1A1ACHE
SCHEMBL11947068 0.82 SMN1; SMN2 (0.40) ESR1ESR2TSHRMLYCDCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3148245-A None JP disclosed
US-20220195189-A1 CYCLIC IMIDE RESIN COMPOSITION, PREPREG, COPPER-CLAD LAMINATE AND PRINTED-WIRING BOARD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-06-23 US disclosed
EP-3561862-A1 METHOD FOR TEMPORARY BONDING WORKPIECE AND ADHESIVE Daxin Materials Corporation (TW) 2019-10-30 EP disclosed
EP-2880080-B1 POLYMERS, POLYMER MEMBRANES AND METHODS OF PRODUCING THE SAME AIR PROD & CHEM (US) 2018-07-04 EP disclosed
US-8821617-B2 Polyimide-co-polybenzoxazole copolymer, preparation method thereof, and gas separation membrane comprising the same INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2014-09-02 US disclosed
US-8821617-B2 Polyimide-co-polybenzoxazole copolymer, preparation method thereof, and gas separation membrane comprising the same INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2014-09-02 US disclosed
US-8753426-B2 Polymers, polymer membranes and methods of producing the same AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-06-17 US disclosed
US-20140033918-A1 Polymers, Polymer Membranes And Methods Of Producing The Same AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-02-06 US disclosed
US-20140033918-A1 Polymers, Polymer Membranes And Methods Of Producing The Same AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-02-06 US disclosed
WO-2014022738-A1 POLYMERS, POLYMER MEMBRANES AND METHODS OF PRODUCING THE SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-02-06 WO disclosed
US-20110065823-A1 POLYIMIDE-CO-POLYBENZOXAZOLE COPOLYMER, PREPARATION METHOD THEREOF, AND GAS SEPARATION MEMBRANE COMPRISING THE SAME Industry-University Cooperation Foundation, Hanyan g University (KR) 2011-03-17 US disclosed
US-20110065823-A1 POLYIMIDE-CO-POLYBENZOXAZOLE COPOLYMER, PREPARATION METHOD THEREOF, AND GAS SEPARATION MEMBRANE COMPRISING THE SAME Industry-University Cooperation Foundation, Hanyan g University (KR) 2011-03-17 US disclosed
WO-2009107889-A1 POLYIMIDE-CO-POLYBENZOXAZOLE COPOLYMER, PREPARATION METHOD THEREOF, AND GAS SEPARATION MEMBRANE COMPRISING THE SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2009-09-03 WO disclosed
US-7285609-B2 Olefin polymerization catalyst system useful for polar monomers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-23 US disclosed
US-7285609-B2 Olefin polymerization catalyst system useful for polar monomers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-23 US disclosed
JP-H03148245-A ASYMMETRIC 2,2-BISARYLHEXAFLUOROPROPANE AND PREPARATION THEREOF CENTRAL GLASS CO LTD 1991-06-25 JP disclosed