SCHEMBL47866

SCHEMBL47866

Cc1ccc(C(c2ccc(C)c(C)c2)(C(F)(F)F)C(F)(F)F)cc1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.46
ESR2 Q92731 2/20 0.46
ALDH1A1 P00352 3/20 0.39
CYP19A1 P11511 2/20 0.35
KIF11 P52732 1/20 0.34
MAPT P10636 2/20 0.33
TP53 P04637 1/20 0.33
MEN1 O00255 1/20 0.33
MITF O75030 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
TSHR P16473 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
PRSS3 P35030 1/20 0.32
LMNA P02545 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29728144 1.00 ESR1 (0.46) ESR1ESR2ALDH1A1CYP19A1KIF11
SCHEMBL13538944 0.98 ESR1 (0.50) ESR1ESR2ALDH1A1CYP19A1KIF11
SCHEMBL13538943 0.91 ESR1 (0.40) ESR1ESR2ALDH1A1CYP19A1KIF11
SCHEMBL9828405 0.91 ESR1 (0.45) ESR1ESR2ALDH1A1CYP19A1KIF11
SCHEMBL11947069 0.89 ESR1 (0.39) ESR1ESR2ALDH1A1CYP19A1KIF11
SCHEMBL10007145 0.89 CYP19A1 (0.45) ESR1ESR2ALDH1A1CYP19A1KIF11
SCHEMBL16253392 0.88 ESR1 (0.53) ESR1ESR2TP53TDP1AR
SCHEMBL15866553 0.88 ESR1 (0.38) ESR1ESR2ALDH1A1CYP19A1
SCHEMBL26037432 0.88 CYP3A4 (0.43) ESR1ESR2ALDH1A1KIF11TP53
SCHEMBL13964423 0.88 ALDH1A1 (0.43) ESR1ESR2ALDH1A1KIF11MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 999 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219455-A Aromatic ring hydrogen-deuterium exchange reaction catalytic system and preparation method of deuterated aromatic hydrocarbon 国科大杭州高等研究院 2024-12-31 CN claimed
WO-2024104062-A1 NITROGEN-CONTAINING HETEROCYCLIC POLYMER, AND POLYMER FILM AND USE THEREOF 武汉立膜科技有限公司 2024-05-23 WO claimed
CN-113004140-B Method for synthesizing 4,4' - (perfluoropropane-2, 2-diyl) diphthalic acid 天津众泰材料科技有限公司 2022-09-30 CN claimed
CN-113004140-A Method for synthesizing 4,4' - (perfluoropropane-2, 2-diyl) diphthalic acid 天津市泰合利华材料科技有限公司 2021-06-22 CN claimed
US-20090156834-A1 PROCESS FOR MAKING 2,2-BIS (3,4-DICARBOXYPHENYL) HEXAFLUOROPROPANE HONEYWELL INTERNATIONAL INC. 2009-06-18 US claimed
US-5194633-A Liquid phase oxidation of corresponding 3,4-dimethyl-compound, polyimides AMOCO CORPORATION (US) 1993-03-16 US claimed
JP-10226681-A None JP disclosed
CN-119233656-A Perovskite film and method for modifying perovskite film at interface 天合光能股份有限公司 2024-12-31 CN disclosed
CN-119219455-A Aromatic ring hydrogen-deuterium exchange reaction catalytic system and preparation method of deuterated aromatic hydrocarbon 国科大杭州高等研究院 2024-12-31 CN disclosed
US-12024605-B2 Polyamide-based composite film and display device comprising same SK MICROWORKS SOLUTIONS CO., LTD. (KR) 2024-07-02 US disclosed
US-20240210827-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR MANUFACTURING CURED RELIEF PATTERN, AND SEMICONDUCTOR APPARATUS ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-06-27 US disclosed
US-20240210827-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR MANUFACTURING CURED RELIEF PATTERN, AND SEMICONDUCTOR APPARATUS ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-06-27 US disclosed
WO-2024136365-A1 POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION AND ELECTRONIC DEVICE COMPRISING SAME 주식회사 엘지화학 2024-06-27 WO disclosed
EP-1389632-A1 Curable fluoropolyether rubber compositions and rubber articles SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-02-18 EP disclosed
JP-H10226681-A PRODUCTION OF FLUORINE-CONTAINING, AROMATIC TETRACARBOXYLIC ACID DIANHYDRIDE SUMIKIN CHEM CO LTD 1998-08-25 JP disclosed
US-5194633-A Liquid phase oxidation of corresponding 3,4-dimethyl-compound, polyimides AMOCO CORPORATION (US) 1993-03-16 US disclosed
US-5194633-A Liquid phase oxidation of corresponding 3,4-dimethyl-compound, polyimides AMOCO CORPORATION (US) 1993-03-16 US disclosed
US-4631335-A MOISTURE AND SOLVENT RESISTANT; AEROSPACE UNITED TECHNOLOGIES CORPORATION (US) 1986-12-23 US disclosed
US-4624727-A BONDING, HOT MELT ADHESIVES UNITED TECHNOLOGIES CORPORATION (US) 1986-11-25 US disclosed
US-4569988-A HOT MELT ADHESIVES UNITED TECHNOLOGIES CORPORATION (US) 1986-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156834-A1 PROCESS FOR MAKING 2,2-BIS (3,4-DICARBOXYPHENYL) HEXAFLUOROPROPANE NOS2, NOS3, NOS1 ESR1 4387/4885ESR2 2970/4885ALDH1A1 2394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.