Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2126761 | 0.83 | CYP1A2 (0.56) | CYP2A6TSHRCYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL19682355 | 0.82 | CYP1A2 (0.54) | CYP2A6TSHRCYP1A2ALDH1A1HSD17B10 | |
| Hydrogen Peroxide SCHEMBL8610674 | 0.80 | CYP1A2 (0.52) | CYP2A6TSHRCYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL18242403 | 0.80 | CYP1A2 (0.52) | CYP2A6TSHRCYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL1707630 | 0.80 | CYP2A6 (0.52) | CYP2A6TSHRCYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL2440482 | 0.80 | TSHR (0.52) | CYP2A6TSHRCYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL16582519 | 0.77 | TSHR (0.48) | CYP2A6TSHRCYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL10634101 | 0.77 | TSHR (0.48) | CYP2A6TSHRCYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL4645643 | 0.77 | L3MBTL1 (0.45) | CYP2A6TSHRCYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL29853736 | 0.77 | L3MBTL1 (0.45) | CYP2A6TSHRCYP1A2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0229100-B1 | METHOD FOR THE PREPARATION OF A MACROMOLECULAR CARRIER LOADED WITH A BIOLOGICALLY ACTIVE SUBSTANCE, PRODUCT THUS OBTAINED AND USE THEREOF | ONCHOLAB AB (SE) | 1991-09-18 | — | — | EP | disclosed |
| US-4868158-A | Method for the production of a macromolecular carrier loaded with a biologically active substance | ONCHOLAB AB (SE) | 1989-09-19 | — | — | US | disclosed |
| WO-1986007540-A1 | METHOD FOR THE PREPARATION OF A MACROMOLECULAR CARRIER LOADED WITH A BIOLOGICALLY ACTIVE SUBSTANCE, PRODUCT THUS OBTAINED AND USE THEREOF | ONCHOLAB AB (SE) | 1986-12-31 | — | — | WO | disclosed |