Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 5/20 | 0.52 |
| ▸ | CTSS | P25774 | 3/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | GNPAT | O15228 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PAM | P19021 | 1/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28068999 | 0.91 | L3MBTL1 (0.56) | L3MBTL1POLBCTSBCTSSCTSL | |
| SCHEMBL6771390 | 0.88 | TACR1 (0.55) | TACR1POLBCTSBCTSSCTSL | |
| SCHEMBL4404729 | 0.86 | L3MBTL1 (0.51) | TACR1L3MBTL1CTSSFOLH1GNPAT | |
| SCHEMBL13811865 | 0.86 | L3MBTL1 (0.51) | TACR1L3MBTL1CTSSFOLH1GNPAT | |
| SCHEMBL9831081 | 0.85 | MEN1 (0.55) | L3MBTL1POLBCTSBCTSSCTSL | |
| SCHEMBL3002363 | 0.85 | NOS2 (0.55) | TACR1L3MBTL1CTSSFOLH1GNPAT | |
| SCHEMBL3002357 | 0.85 | NOS2 (0.55) | TACR1L3MBTL1CTSSFOLH1GNPAT | |
| SCHEMBL805204 | 0.84 | POLB (0.51) | L3MBTL1POLBCTSBCTSSCTSL | |
| SCHEMBL11132296 | 0.84 | POLB (0.51) | L3MBTL1POLBCTSBCTSSCTSL | |
| SCHEMBL11132299 | 0.84 | POLB (0.51) | L3MBTL1POLBCTSBCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |