Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | CTSG | P08311 | 2/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.43 |
| ▸ | CMA1 | P23946 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828728 | 1.00 | ALDH1A1 (0.48) | ALDH1A1RAB9APOLBPRSS1CTSG | |
| SCHEMBL9830134 | 0.82 | PLK1 (0.54) | ALDH1A1RAB9AHPGDSMN1; SMN2NPC1 | |
| SCHEMBL9830138 | 0.82 | PLK1 (0.54) | ALDH1A1RAB9AHPGDSMN1; SMN2NPC1 | |
| SCHEMBL10659183 | 0.81 | PPARG (0.52) | RAB9AGAATSHRSMN1; SMN2LMNA | |
| SCHEMBL10659190 | 0.81 | PPARG (0.52) | RAB9AGAATSHRSMN1; SMN2LMNA | |
| SCHEMBL9830870 | 0.79 | POLB (0.49) | ALDH1A1POLBHPGDCYP1A2KMT2A | |
| SCHEMBL9830875 | 0.79 | POLB (0.49) | ALDH1A1POLBHPGDCYP1A2KMT2A | |
| SCHEMBL9830170 | 0.78 | KMT2A (0.50) | ALDH1A1RAB9APOLBGAASMN1; SMN2 | |
| SCHEMBL9830174 | 0.78 | KMT2A (0.50) | ALDH1A1RAB9APOLBGAASMN1; SMN2 | |
| SCHEMBL407184 | 0.78 | POLB (0.46) | ALDH1A1RAB9APOLBGAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |