Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 3/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.51 |
| ▸ | RARB | P10826 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830134 | 1.00 | PLK1 (0.54) | PLK1TRPV1RARBKDM4EALDH1A1 | |
| SCHEMBL10659190 | 0.84 | PPARG (0.52) | PLK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9828728 | 0.82 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD17B10NPC1RAB9A | |
| SCHEMBL9828729 | 0.82 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD17B10NPC1RAB9A | |
| SCHEMBL24534839 | 0.79 | PLK1 (0.59) | PLK1TRPV1RARBKDM4EALDH1A1 | |
| SCHEMBL24534825 | 0.74 | PLK1 (0.56) | PLK1TRPV1RARBALDH1A1THRA | |
| SCHEMBL24534804 | 0.74 | RARB (0.54) | PLK1TRPV1RARBALDH1A1THRA | |
| SCHEMBL6958590 | 0.71 | PLK1 (1.00) | PLK1TRPV1RARBKDM4EALDH1A1 | |
| SCHEMBL6919330 | 0.71 | PLK1 (0.74) | PLK1TRPV1RARBKDM4ETHRA | |
| SCHEMBL19443009 | 0.71 | PLK1 (0.74) | PLK1TRPV1RARBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |