Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29090804 | 0.82 | LMNA (0.72) | LMNAMAPK1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5657986 | 0.82 | LMNA (0.72) | LMNAMAPK1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30594162 | 0.82 | LMNA (0.72) | LMNAMAPK1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30481056 | 0.82 | LMNA (0.72) | LMNAMAPK1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19071835 | 0.82 | LMNA (0.57) | LMNAMAPK1ALDH1A1CA1CA2 | |
| SCHEMBL10865398 | 0.81 | MAPK1 (0.86) | LMNAMAPK1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5655215 | 0.81 | MAPK1 (0.86) | LMNAMAPK1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1231651 | 0.81 | MAPK1 (0.86) | LMNAMAPK1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10659200 | 0.81 | MAPK1 (0.86) | LMNAMAPK1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21320455 | 0.81 | LMNA (0.70) | LMNAMAPK1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |