Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 4/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9771136 | 0.94 | HRH4 (0.37) | HRH4HRH3 | |
| Hydrochloric Acid SCHEMBL10368540 | 0.92 | GBA1 (0.40) | GBA1SSTR4HRH4HRH3SSTR2 | |
| Hydrochloric Acid SCHEMBL10369610 | 0.85 | HRH4 (0.41) | GBA1SSTR4HRH4HRH3 | |
| SCHEMBL9828418 | 0.85 | SSTR4 (0.42) | SSTR4SSTR2 | |
| SCHEMBL10374977 | 0.84 | GBA1 (0.36) | GBA1HRH4HRH3 | |
| Hydrochloric Acid SCHEMBL10369460 | 0.83 | GBA1 (0.39) | GBA1SSTR4HRH4HRH3 | |
| Hydrochloric Acid SCHEMBL10369553 | 0.83 | HRH4 (0.38) | GBA1HRH4HRH3 | |
| SCHEMBL7288384 | 0.81 | SCN5A (0.34) | HRH4 | |
| SCHEMBL9828331 | 0.81 | MTNR1A (0.38) | — | |
| SCHEMBL9867126 | 0.80 | HRH4 (0.47) | HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302896-B1 | N-(W-SUBSTITUTED ALKYL)-N'-[(IMIDAZOLE-4-YL)ALKYL]GUANIDINE | CEDONA PHARMACEUTICALS B.V. (NL) | 1991-08-14 | — | — | EP | claimed |