Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 2/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288663 | 0.93 | SCN5A (0.34) | SCN5ASCN2AHRH4ADRA2AADRA2B | |
| SCHEMBL9771136 | 0.87 | HRH4 (0.37) | HRH4HRH2 | |
| SCHEMBL9828331 | 0.82 | MTNR1A (0.38) | — | |
| SCHEMBL9828857 | 0.81 | GBA1 (0.37) | HRH4 | |
| Hydrochloric Acid SCHEMBL10369610 | 0.79 | HRH4 (0.41) | HRH4HRH2 | |
| SCHEMBL7288371 | 0.79 | ADRA2A (0.35) | ADRA2AADRA2BADRA2C | |
| SCHEMBL9829117 | 0.77 | KCNH2 (0.41) | — | |
| SCHEMBL9828418 | 0.77 | SSTR4 (0.42) | ADRA2AADRA2BADRA2C | |
| SCHEMBL9828167 | 0.76 | NPY1R (0.39) | — | |
| Hydrochloric Acid SCHEMBL10371446 | 0.75 | HRH4 (0.40) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262448-B1 | IMIDAZOLYLGUANIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | HEUMANN PHARMA GMBH & CO (DE) | 1991-12-18 | — | — | EP | disclosed |