Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TYMP | P19971 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9797058 | 1.00 | ALDH1A1 (0.58) | ALDH1A1KDM4ESMN1; SMN2KMT2AATM | |
| SCHEMBL31087177 | 0.94 | ALDH1A1 (0.65) | ALDH1A1KDM4ECYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL8515731 | 0.89 | KDM4E (0.60) | ALDH1A1KDM4ECYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL10857521 | 0.82 | KDM4E (0.63) | ALDH1A1KDM4ESMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL9797052 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KDM4ESMN1; SMN2KMT2AATM | |
| SCHEMBL5108684 | 0.81 | KDM4E (0.58) | ALDH1A1KDM4ECYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL30064990 | 0.78 | KMT2A (0.67) | ALDH1A1KDM4ESMN1; SMN2KMT2AATM | |
| SCHEMBL22587273 | 0.77 | CYP2C9 (0.58) | ALDH1A1KDM4EATMCYP2C9CYP2C19 | |
| SCHEMBL22587316 | 0.76 | KDM4E (0.57) | ALDH1A1KDM4EKMT2ACYP2C9CYP2C19 | |
| SCHEMBL10870720 | 0.74 | HTT (0.44) | ALDH1A1KDM4EKMT2AATMCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422178-A1 | PYRIMIDINE DERIVATIVES. | ICI PLC (GB) | 1991-04-17 | — | — | EP | disclosed |