Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9797058 | 0.94 | ALDH1A1 (0.58) | ALDH1A1KDM4ECYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL9828879 | 0.94 | ALDH1A1 (0.58) | ALDH1A1KDM4ECYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL8515731 | 0.92 | KDM4E (0.60) | ALDH1A1KDM4ECYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL10857521 | 0.84 | KDM4E (0.63) | ALDH1A1KDM4ECYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL5108684 | 0.83 | KDM4E (0.58) | ALDH1A1KDM4ECYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL10870720 | 0.80 | HTT (0.44) | ALDH1A1KDM4ECYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL22587273 | 0.80 | CYP2C9 (0.58) | ALDH1A1KDM4ECYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL22587316 | 0.78 | KDM4E (0.57) | ALDH1A1KDM4ECYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL10735952 | 0.77 | ALDH1A1 (0.73) | ALDH1A1KDM4ECYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL31087180 | 0.76 | KDM4E (0.55) | ALDH1A1KDM4EHTTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240307394-A1 | MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR D AND RELATED PRODUCTS AND METHODS | INCYTE CORPORATION | 2024-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240307394-A1 | MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR D AND RELATED PRODUCTS AND METHODS | MRGPRX1, MRGPRX4, MRGPRX2 | ALDH1A1 3659/4885KDM4E 4555/4885CYP2C9 2506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.