Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 3/20 | 0.33 |
| ▸ | CTSD | P07339 | 2/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829535 | 0.85 | RAB9A (0.41) | RAB9ASCN9ACYP2C19CYP2C9RXFP1 | |
| SCHEMBL9829359 | 0.84 | RAB9A (0.41) | RAB9ASCN9ARXFP1BCHEACHE | |
| SCHEMBL9830150 | 0.83 | RAB9A (0.39) | RAB9ASCN9ACYP2C19CYP2C9RXFP1 | |
| Oxalic Acid SCHEMBL9829862 | 0.80 | TP53 (0.41) | RAB9ASCN9ARXFP1BCHEACHE | |
| SCHEMBL9831340 | 0.76 | EBP (0.45) | — | |
| Oxalic Acid SCHEMBL9831243 | 0.73 | SMPD1 (0.47) | ALDH1A1SMPD1MAPT | |
| Hydrochloric Acid SCHEMBL9829644 | 0.73 | HRH1 (0.41) | RAB9A | |
| Oxalic Acid SCHEMBL9831824 | 0.73 | SMPD1 (0.46) | ALDH1A1SMPD1MAPT | |
| Oxalic Acid SCHEMBL9831327 | 0.71 | CYP2D6 (0.45) | CYP2C19CYP2C9MEN1KMT2ALMNA | |
| SCHEMBL9831128 | 0.70 | CYP2C19 (0.42) | RAB9ASCN9ACYP2C19CYP2C9RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233291-B1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4739050-A | CALCIUM ANTAGONIST, ANTICOAGULANT | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0233291-A1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1987-08-26 | — | — | EP | disclosed |