Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.49 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.49 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 6/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7748966 | 0.82 | ERCC1 (0.55) | ERCC1ERCC4GRM7POLBGPR88 | |
| SCHEMBL17307874 | 0.82 | ERCC1 (0.55) | ERCC1ERCC4GRM7POLBGPR88 | |
| SCHEMBL6137585 | 0.78 | MME (0.62) | ERCC1ERCC4GRM7POLBMME | |
| SCHEMBL10138151 | 0.76 | PKM (0.58) | ERCC1ERCC4GRM7POLBGPR88 | |
| SCHEMBL19523017 | 0.76 | PKM (0.58) | ERCC1ERCC4GRM7POLBGPR88 | |
| SCHEMBL9829224 | 0.76 | SLC22A6 (0.48) | — | |
| SCHEMBL14540295 | 0.76 | ERCC1 (0.52) | ERCC1ERCC4MME | |
| SCHEMBL3200580 | 0.76 | ERCC1 (0.52) | ERCC1ERCC4MME | |
| SCHEMBL9830287 | 0.73 | NPC1 (0.62) | POLB | |
| SCHEMBL22051371 | 0.73 | ERCC1 (0.54) | ERCC1ERCC4GRM7POLBGPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |