Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.55 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13059171 | 0.90 | PTGS2 (0.59) | ERCC1ERCC4KMT2AMEN1ALDH1A1 | |
| SCHEMBL17307874 | 0.89 | ERCC1 (0.55) | ERCC1ERCC4KMT2AMEN1GRM7 | |
| SCHEMBL15709156 | 0.85 | CNR1 (0.59) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL13765364 | 0.84 | NAAA (0.58) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL10138151 | 0.83 | PKM (0.58) | ERCC1ERCC4KMT2AMEN1ALDH1A1 | |
| SCHEMBL19523017 | 0.83 | PKM (0.58) | ERCC1ERCC4KMT2AMEN1ALDH1A1 | |
| SCHEMBL4214155 | 0.82 | KMT2A (0.50) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL4989142 | 0.82 | KMT2A (0.50) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL6784092 | 0.82 | CHRM1 (0.50) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL9828973 | 0.82 | ERCC1 (0.49) | ERCC1ERCC4GRM7POLBGPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480941-B1 | UREA DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | AMBRILIA BIOPHARMA INC (CA) | 2011-01-26 | — | — | EP | disclosed |
| US-6528532-B1 | Benzenesulfonamide group | PHARMACOR INC. (CA) | 2003-03-04 | — | — | US | disclosed |