Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828979 | 1.00 | NPSR1 (0.57) | NPSR1TAS1R3TAS1R1CA1CA2 | |
| SCHEMBL7410707 | 0.89 | NPSR1 (0.71) | NPSR1TAS1R3TAS1R1CA1CA2 | |
| SCHEMBL5838728 | 0.89 | NPSR1 (0.71) | NPSR1TAS1R3TAS1R1CA1CA2 | |
| SCHEMBL10659164 | 0.86 | NPSR1 (0.56) | NPSR1TAS1R3TAS1R1CA1CA2 | |
| SCHEMBL10659171 | 0.86 | NPSR1 (0.56) | NPSR1TAS1R3TAS1R1CA1CA2 | |
| SCHEMBL11509188 | 0.85 | NPSR1 (0.66) | NPSR1TAS1R3TAS1R1CA1CA2 | |
| SCHEMBL21274381 | 0.84 | CA2 (0.64) | NPSR1TAS1R3TAS1R1CA1CA2 | |
| SCHEMBL21274384 | 0.84 | CA2 (0.64) | NPSR1TAS1R3TAS1R1CA1CA2 | |
| SCHEMBL5637591 | 0.82 | CA2 (0.58) | TAS1R3TAS1R1CA1CA2PLK1 | |
| SCHEMBL9829827 | 0.82 | CA2 (0.58) | TAS1R3TAS1R1CA1CA2PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |