Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.71 |
| ▸ | PPARG | P37231 | 2/20 | 0.63 |
| ▸ | PPARA | Q07869 | 1/20 | 0.63 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 4/20 | 0.60 |
| ▸ | CA1 | P00915 | 3/20 | 0.60 |
| ▸ | MMP2 | P08253 | 2/20 | 0.57 |
| ▸ | MMP9 | P14780 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | MMP7 | P09237 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5838728 | 1.00 | NPSR1 (0.71) | NPSR1PPARGPPARADGAT1CA2 | |
| SCHEMBL11509188 | 0.95 | NPSR1 (0.66) | NPSR1PPARGPPARADGAT1CA2 | |
| SCHEMBL9828979 | 0.89 | NPSR1 (0.57) | NPSR1PPARGPPARADGAT1CA2 | |
| SCHEMBL9828975 | 0.89 | NPSR1 (0.57) | NPSR1PPARGPPARADGAT1CA2 | |
| SCHEMBL10659164 | 0.88 | NPSR1 (0.56) | NPSR1PPARGPPARADGAT1CA2 | |
| SCHEMBL10659171 | 0.88 | NPSR1 (0.56) | NPSR1PPARGPPARADGAT1CA2 | |
| SCHEMBL15906297 | 0.87 | ALDH1A1 (0.60) | NPSR1DGAT1CA2CA1ALDH1A1 | |
| SCHEMBL21274384 | 0.85 | CA2 (0.64) | NPSR1PPARGPPARADGAT1CA2 | |
| SCHEMBL21274381 | 0.85 | CA2 (0.64) | NPSR1PPARGPPARADGAT1CA2 | |
| SCHEMBL11509003 | 0.84 | NPSR1 (0.68) | NPSR1PPARGPPARADGAT1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112261939-A | Granzyme B directed imaging and therapy | 塞托赛特生物制药股份有限公司 | 2021-01-22 | — | — | CN | disclosed |
| WO-2018011230-A1 | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA AGONISTS, METHOD OF PREPARATION AND USES THEREOF | UNIVERSITE D'AIX-MARSEILLE (FR) | 2018-01-18 | — | — | WO | disclosed |
| EP-1140846-A1 | ASPARTIC PROTEASE INHIBITORS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040558-A1 | ASPARTIC PROTEASE INHIBITORS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2000-07-13 | — | — | WO | disclosed |