SCHEMBL9829019

SCHEMBL9829019

C=C(COC(=O)CCCCCCOS(C)(=O)=O)COC(=O)NCCCCCCCCCCCCCCCCCC

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ACHE P22303 13/20 0.45
EPHX2 P34913 2/20 0.45
PAM P19021 2/20 0.42
DGKA P23743 1/20 0.41
EPHX1 P07099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9827724 0.88 ACHE (0.47) ACHEEPHX2EPHX1
SCHEMBL9828474 0.88 ACHE (0.47) ACHEEPHX2EPHX1
SCHEMBL10451440 0.87 ACHE (0.46) ACHEEPHX2EPHX1
SCHEMBL9828958 0.83 PAM (0.48) ACHEEPHX2PAMDGKAEPHX1
SCHEMBL9830422 0.83 PAM (0.48) ACHEEPHX2PAMDGKAEPHX1
SCHEMBL9827743 0.83 PAM (0.48) ACHEEPHX2PAMDGKAEPHX1
SCHEMBL9828525 0.83 PAM (0.48) ACHEEPHX2PAMDGKAEPHX1
SCHEMBL9828118 0.83 PAM (0.48) ACHEEPHX2PAMDGKAEPHX1
SCHEMBL9828423 0.83 PAM (0.48) ACHEEPHX2PAMDGKAEPHX1
SCHEMBL9829281 0.83 PAM (0.48) ACHEEPHX2PAMDGKAEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0458823-A1 A PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE POLYSUBSTITUTED 1,4-DIHYDROPYRIDINES. BOEHRINGER MANNHEIM ITALIA (IT) 1991-12-04 EP disclosed
EP-0247201-B1 PROPANE-1,3-DIOL DERIVATIVES, A METHOD FOR THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) 1991-05-15 EP disclosed
US-4945098-A Novel propane-1,3-diol derivatives and use LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) 1990-07-31 US disclosed
EP-0247201-A1 PROPANE-1,3-DIOL DERIVATIVES, A METHOD FOR THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION. LEO PHARM PROD LTD (DK) 1987-12-02 EP disclosed
WO-1987003281-A1 PROPANE-1,3-DIOL DERIVATIVES, A METHOD FOR THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) 1987-06-04 WO disclosed