Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.61 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.61 |
| ▸ | FAAH | O00519 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.50 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.49 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.47 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.45 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829119 | 1.00 | PLA2G2A (0.61) | PLA2G2APLA2G5FAAHMEN1KMT2A | |
| SCHEMBL4383689 | 0.92 | FAAH (0.66) | PLA2G2APLA2G5FAAHSMN1; SMN2SLC6A5 | |
| SCHEMBL4383693 | 0.92 | FAAH (0.66) | PLA2G2APLA2G5FAAHSMN1; SMN2SLC6A5 | |
| SCHEMBL9666571 | 0.89 | PLA2G2A (0.71) | PLA2G2APLA2G5FAAHMEN1KMT2A | |
| SCHEMBL7773487 | 0.89 | PLA2G2A (0.71) | PLA2G2APLA2G5FAAHMEN1KMT2A | |
| SCHEMBL25192254 | 0.89 | PLA2G2A (0.71) | PLA2G2APLA2G5FAAHMEN1KMT2A | |
| SCHEMBL15649018 | 0.89 | PLA2G2A (0.71) | PLA2G2APLA2G5FAAHMEN1KMT2A | |
| SCHEMBL15697666 | 0.89 | PLA2G2A (0.71) | PLA2G2APLA2G5FAAHMEN1KMT2A | |
| SCHEMBL9666963 | 0.89 | PLA2G2A (0.71) | PLA2G2APLA2G5FAAHMEN1KMT2A | |
| SCHEMBL543200 | 0.89 | PLA2G2A (0.71) | PLA2G2APLA2G5FAAHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |