Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 8/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | USP1 | O94782 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829470 | 0.86 | HSD11B1 (0.50) | HSD11B1NPC1RAB9ANR1H2NR1H3 | |
| SCHEMBL9830541 | 0.82 | HSD11B1 (0.58) | HSD11B1NPC1RAB9ANR1H2NR1H3 | |
| SCHEMBL9830876 | 0.81 | HSD11B1 (0.51) | HSD11B1TRPA1 | |
| SCHEMBL11589724 | 0.79 | NR1H2 (0.61) | NPC1RAB9ANR1H2NR1H3HTT | |
| SCHEMBL9829823 | 0.79 | HSD11B1 (0.62) | HSD11B1TRPA1AHR | |
| SCHEMBL9830814 | 0.79 | HSD11B1 (0.54) | HSD11B1NPC1RAB9ANR1H2NR1H3 | |
| SCHEMBL9832170 | 0.79 | HSD11B1 (0.54) | HSD11B1TRPA1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9832924 | 0.79 | HSD11B1 (0.48) | HSD11B1CYP3A4CYP2D6CYP2C19KDM4E | |
| SCHEMBL9829855 | 0.78 | HSD11B1 (0.53) | HSD11B1TRPA1 | |
| Fepitrizol SCHEMBL2107850 | 0.78 | USP1 (0.47) | NPC1RAB9ANR1H2NR1H3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185256-B1 | TRIAZOLE DERIVATES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | CIBA-GEIGY AG (CH) | 1991-01-30 | — | — | EP | claimed |
| EP-0185256-A2 | Triazole derivates, their preparation and their use as pesticides | CIBA-GEIGY AG (CH) | 1986-06-25 | — | — | EP | claimed |
| EP-0185256-B1 | TRIAZOLE DERIVATES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | CIBA-GEIGY AG (CH) | 1991-01-30 | — | — | EP | disclosed |
| US-4788210-A | PESTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |