Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2678250 | 1.00 | HTT (0.64) | HTTKMT2AALDH1A1GLATGM2 | |
| SCHEMBL9830417 | 0.99 | HTT (0.66) | HTTKMT2AALDH1A1GLATGM2 | |
| SCHEMBL7009466 | 0.95 | HTT (0.72) | HTTKMT2AALDH1A1GLAPOLB | |
| SCHEMBL9828159 | 0.89 | HTT (0.58) | HTTKMT2AALDH1A1GLANPC1 | |
| SCHEMBL9829906 | 0.86 | HTT (0.68) | HTTKMT2ATGM2FOLH1 | |
| SCHEMBL9830472 | 0.86 | HTT (0.71) | HTTKMT2ATGM2FOLH1 | |
| SCHEMBL9830594 | 0.85 | HTT (0.69) | HTTKMT2ATGM2FOLH1L3MBTL1 | |
| SCHEMBL2876850 | 0.85 | HTT (0.88) | HTTKMT2ATGM2FOLH1 | |
| SCHEMBL4858734 | 0.85 | HTT (0.88) | HTTKMT2ATGM2FOLH1 | |
| SCHEMBL4857273 | 0.85 | HTT (0.88) | HTTKMT2ATGM2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |