Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7009466 | 0.92 | HTT (0.72) | HTTALDH1A1GLAKMT2AFFAR1 | |
| SCHEMBL9830417 | 0.90 | HTT (0.66) | HTTALDH1A1GLAKMT2AFFAR1 | |
| SCHEMBL9829454 | 0.89 | HTT (0.64) | HTTALDH1A1GLAKMT2AFFAR1 | |
| SCHEMBL2678250 | 0.89 | HTT (0.64) | HTTALDH1A1GLAKMT2AFFAR1 | |
| SCHEMBL8441435 | 0.85 | ALDH1A1 (0.60) | HTTALDH1A1GLAKMT2AFFAR1 | |
| SCHEMBL9829717 | 0.85 | HTT (0.61) | HTTKMT2AMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL11526146 | 0.85 | ALDH1A1 (0.60) | HTTALDH1A1GLAKMT2AATM | |
| SCHEMBL8439121 | 0.84 | ALDH1A1 (0.58) | HTTALDH1A1GLAKMT2AATM | |
| SCHEMBL6750273 | 0.84 | ALDH1A1 (0.58) | HTTALDH1A1GLAKMT2AATM | |
| SCHEMBL6878893 | 0.83 | HTT (0.57) | HTTALDH1A1KMT2AL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |