Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 0.55 |
| ▸ | CA1 | P00915 | 7/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829504 | 1.00 | CA2 (0.55) | CA2CA1CA12CA9NPC1 | |
| SCHEMBL9831590 | 0.88 | CA2 (0.53) | CA2CA1CA12CA9USP2 | |
| SCHEMBL9831250 | 0.88 | CA2 (0.53) | CA2CA1CA12CA9USP2 | |
| SCHEMBL9831247 | 0.88 | CA2 (0.53) | CA2CA1CA12CA9USP2 | |
| SCHEMBL9831597 | 0.88 | CA2 (0.53) | CA2CA1CA12CA9USP2 | |
| SCHEMBL9830017 | 0.87 | ALDH1A1 (0.53) | CA2CA1CA12CA9NPC1 | |
| SCHEMBL4955422 | 0.87 | ALDH1A1 (0.53) | CA2CA1CA12CA9NPC1 | |
| SCHEMBL9432949 | 0.86 | CA2 (0.72) | CA2CA1CA12CA9USP2 | |
| SCHEMBL9830498 | 0.86 | CA2 (0.72) | CA2CA1CA12CA9USP2 | |
| SCHEMBL9828943 | 0.82 | CA2 (0.52) | CA2CA1CA12CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |