Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 12/20 | 0.70 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.55 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | GNPAT | O15228 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829527 | 1.00 | NOD1 (0.70) | NOD1SLC6A5FAAHGNPATMEN1 | |
| SCHEMBL9829501 | 0.93 | NOD1 (0.81) | NOD1SLC6A5FAAHMEN1MAPK1 | |
| SCHEMBL22684646 | 0.93 | NOD1 (0.81) | NOD1SLC6A5FAAHMEN1MAPK1 | |
| SCHEMBL8293340 | 0.93 | NOD1 (0.81) | NOD1SLC6A5FAAHMEN1MAPK1 | |
| SCHEMBL18560507 | 0.93 | NOD1 (0.81) | NOD1SLC6A5FAAHMEN1MAPK1 | |
| SCHEMBL24787612 | 0.93 | NOD1 (0.81) | NOD1SLC6A5FAAHMEN1MAPK1 | |
| SCHEMBL8293954 | 0.93 | NOD1 (0.81) | NOD1SLC6A5FAAHMEN1MAPK1 | |
| SCHEMBL8515462 | 0.93 | NOD1 (0.81) | NOD1SLC6A5FAAHMEN1MAPK1 | |
| SCHEMBL15649578 | 0.93 | NOD1 (0.81) | NOD1SLC6A5FAAHMEN1MAPK1 | |
| SCHEMBL9829505 | 0.93 | NOD1 (0.81) | NOD1SLC6A5FAAHMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |