SCHEMBL8293340

SCHEMBL8293340

CCCCCCCCCCCCCCCCCC(=O)NC(CCC)C(=O)O

nearest known ligand 0.81

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ NOD1 Q9Y239 11/20 0.81
▸ SLC6A5 Q9Y345 2/20 0.63
▸ FAAH O00519 3/20 0.59
▸ MEN1 O00255 1/20 0.59
▸ MAPK1 P28482 1/20 0.59
▸ KMT2A Q03164 1/20 0.59
▸ PLA2G2C Q5R387 1/20 0.57
▸ EPHX2 P34913 1/20 0.53
▸ DNM1 Q05193 1/20 0.53
▸ PLA2G10 O15496 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14453635 1.00 NOD1 (0.81) NOD1SLC6A5FAAHMEN1MAPK1
SCHEMBL8293954 1.00 NOD1 (0.81) NOD1SLC6A5FAAHMEN1MAPK1
SCHEMBL9829501 1.00 NOD1 (0.81) NOD1SLC6A5FAAHMEN1MAPK1
SCHEMBL18560507 1.00 NOD1 (0.81) NOD1SLC6A5FAAHMEN1MAPK1
SCHEMBL8515462 1.00 NOD1 (0.81) NOD1SLC6A5FAAHMEN1MAPK1
SCHEMBL24787612 1.00 NOD1 (0.81) NOD1SLC6A5FAAHMEN1MAPK1
SCHEMBL9829505 1.00 NOD1 (0.81) NOD1SLC6A5FAAHMEN1MAPK1
SCHEMBL15649578 1.00 NOD1 (0.81) NOD1SLC6A5FAAHMEN1MAPK1
SCHEMBL22684646 1.00 NOD1 (0.81) NOD1SLC6A5FAAHMEN1MAPK1
SCHEMBL8293270 1.00 NOD1 (0.81) NOD1SLC6A5FAAHMEN1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220119473-A1 ACYLATED OXYNTOMODULIN PEPTIDE ANALOG DONG-A ST CO., LTD. (KR) 2022-04-21 — — US disclosed
EP-2932981-B1 Albumin-binding derivatives of GLP-1 NOVO NORDISK AS (DK) 2021-06-16 — — EP disclosed
CN-107624066-A The cosmetic treatment method of hair 莱雅公司 2018-01-23 — — CN disclosed
US-20160108102-A1 Novel GLP-1 Derivatives NOVO NORDISK AS (DK) 2016-04-21 — — US disclosed
EP-2932981-A2 Albumin-binding derivatives of GLP-1 NOVO NORDISK A/S (DK) 2015-10-21 — — EP disclosed
US-20130244931-A1 Novel GLP-1 Derivatives NOVO NORDISK AS (DK) 2013-09-19 — — US disclosed
US-20130053315-A1 NOVEL GLP-1 DERIVATIVES NOVO NORDISK A/S 2013-02-28 — — US disclosed
US-20130040884-A1 ALBUMIN-BINDING CONJUGATES COMPRISING FATTY-ACID AND PEG NOVO NORDISK A/S 2013-02-14 — — US disclosed
US-20100305032-A1 Novel GLP-1 Derivatives NOVO NORDISK A/S (DK) 2010-12-02 — — US disclosed
US-20100305032-A1 Novel GLP-1 Derivatives NOVO NORDISK A/S (DK) 2010-12-02 — — US disclosed
US-20070203058-A1 Novel Glp-1 Derivatives NOVO NORDISK A/S (DK) 2007-08-30 — — US disclosed
US-20070203058-A1 Novel Glp-1 Derivatives NOVO NORDISK A/S (DK) 2007-08-30 — — US disclosed
WO-2005027978-A2 ALBUMIN-BINDING DERIVATIVES OF THERAPEUTIC PEPTIDES NOVO NORDISK A/S (DK) 2005-03-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130040884-A1 ALBUMIN-BINDING CONJUGATES COMPRISING FATTY-ACID AND PEG FABP1, FABP2, FABP4 NOD1 3894/4885SLC6A5 2901/4885FAAH 112/4885
US-20130053315-A1 NOVEL GLP-1 DERIVATIVES GLP1R, GIPR, IAPP NOD1 575/4885SLC6A5 2059/4885FAAH 1323/4885
US-20160108102-A1 Novel GLP-1 Derivatives GLP1R, GIPR, IAPP NOD1 575/4885SLC6A5 2059/4885FAAH 1323/4885
US-20100305032-A1 Novel GLP-1 Derivatives GLP1R, GIPR, IAPP NOD1 575/4885SLC6A5 2059/4885FAAH 1323/4885
US-20070203058-A1 Novel Glp-1 Derivatives GLP1R, GIPR, NPY4R NOD1 410/4885SLC6A5 2385/4885FAAH 3270/4885
US-20220119473-A1 ACYLATED OXYNTOMODULIN PEPTIDE ANALOG GLP1R, GIPR, GPR119 NOD1 386/4885SLC6A5 4071/4885FAAH 235/4885
US-20130244931-A1 Novel GLP-1 Derivatives GLP1R, GIPR, IAPP NOD1 575/4885SLC6A5 2059/4885FAAH 1323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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