Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829581 | 1.00 | CXCR2 (0.42) | CXCR2RECQLALDH1A1MAPTKCNN4 | |
| SCHEMBL18112805 | 0.86 | ALDH1A1 (0.40) | RECQLALDH1A1MAPTKCNN4CYP2C19 | |
| SCHEMBL16245171 | 0.86 | ESR1 (0.44) | CXCR2RECQLALDH1A1MAPTCYP1A2 | |
| SCHEMBL10857937 | 0.86 | MAPT (0.39) | RECQLALDH1A1MAPTKCNN4CYP2C19 | |
| SCHEMBL10857941 | 0.86 | MAPT (0.39) | RECQLALDH1A1MAPTKCNN4CYP2C19 | |
| SCHEMBL18112741 | 0.84 | KMT2A (0.43) | CXCR2RECQLMAPTKCNN4CYP2C19 | |
| SCHEMBL193093 | 0.83 | KCNN4 (0.44) | CXCR2ALDH1A1MAPTKCNN4CYP2C19 | |
| SCHEMBL3923935 | 0.83 | POLB (0.50) | CXCR2CYP2C19HSD17B10LMNAHDAC1 | |
| SCHEMBL4450821 | 0.81 | KCNN4 (0.43) | CXCR2ALDH1A1MAPTKCNN4CYP2C19 | |
| SCHEMBL14306296 | 0.81 | KCNN4 (0.43) | CXCR2ALDH1A1MAPTKCNN4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |