Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829469 | 0.84 | CNR1 (0.41) | CYP2C19CYP2C9MAPTALDH1A1PKM | |
| SCHEMBL9831997 | 0.81 | BCHE (0.44) | BCHEMAPTNPSR1ALDH1A1PKM | |
| SCHEMBL9828823 | 0.81 | BCHE (0.42) | BCHEMAPTNPSR1ALDH1A1PKM | |
| SCHEMBL9828818 | 0.77 | BCHE (0.41) | BCHEMAPTNPSR1ALDH1A1PKM | |
| SCHEMBL9830720 | 0.74 | MEN1 (0.45) | BCHECYP2C19CYP2C9MAPTNPSR1 | |
| SCHEMBL11929623 | 0.73 | MAPT (0.56) | BCHECYP2C19MAPTNPSR1ALDH1A1 | |
| SCHEMBL11929218 | 0.70 | MAPT (0.41) | BCHEMAPTNPSR1ALDH1A1PKM | |
| SCHEMBL9830517 | 0.69 | KDM4E (0.37) | BCHEMAPTNPSR1ALDH1A1PKM | |
| SCHEMBL7993447 | 0.68 | CYP2C19 (0.48) | CYP2C19CYP2C9ALDH1A1NPC1RAB9A | |
| SCHEMBL10990789 | 0.67 | NOX1 (0.63) | BCHEMAPTALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233291-B1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4739050-A | CALCIUM ANTAGONIST, ANTICOAGULANT | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0233291-A1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1987-08-26 | — | — | EP | disclosed |