Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831997 | 0.88 | BCHE (0.44) | BCHEMAPTALDH1A1PKMMEN1 | |
| SCHEMBL9831087 | 0.87 | CNR1 (0.37) | MAPTALDH1A1PKMMEN1KMT2A | |
| SCHEMBL9830507 | 0.82 | NQO2 (0.39) | BCHEMAPTALDH1A1PKMMEN1 | |
| SCHEMBL9829068 | 0.80 | MEN1 (0.33) | MAPTALDH1A1PKMMEN1KMT2A | |
| SCHEMBL9829070 | 0.78 | PDE3B (0.36) | MAPT | |
| SCHEMBL9829616 | 0.77 | BCHE (0.44) | BCHEMAPTALDH1A1PKMMEN1 | |
| SCHEMBL9828823 | 0.74 | BCHE (0.42) | BCHEMAPTALDH1A1PKMMEN1 | |
| SCHEMBL9828953 | 0.71 | CNR1 (0.42) | BCHEMAPTALDH1A1PKMHTT | |
| SCHEMBL7114679 | 0.69 | BCHE (0.41) | BCHEMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11929623 | 0.69 | MAPT (0.56) | BCHEMAPTALDH1A1PKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233291-B1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4739050-A | CALCIUM ANTAGONIST, ANTICOAGULANT | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0233291-A1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1987-08-26 | — | — | EP | disclosed |