Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 9/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 3/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 3/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830681 | 0.78 | ALDH1A1 (0.49) | MAPTKMT2AALDH1A1MEN1RAB9A | |
| SCHEMBL3206574 | 0.75 | MAPT (0.60) | MAPTHSD17B10KMT2AALDH1A1MEN1 | |
| SCHEMBL9829059 | 0.71 | MEN1 (0.59) | MAPTKMT2AALDH1A1MEN1RAB9A | |
| SCHEMBL653613 | 0.70 | MAPT (1.00) | MAPTHSD17B10KMT2AALDH1A1MEN1 | |
| SCHEMBL3065254 | 0.70 | MAPT (0.57) | MAPTHSD17B10KMT2AALDH1A1MEN1 | |
| SCHEMBL1677400 | 0.69 | MAPT (0.60) | MAPTHSD17B10KMT2AALDH1A1MEN1 | |
| SCHEMBL14267941 | 0.67 | MAPT (0.53) | MAPTHSD17B10KMT2AALDH1A1MEN1 | |
| Bromide SCHEMBL11063894 | 0.67 | ATP4A (0.59) | MAPTHSD17B10RAB9ANPC1GFER | |
| SCHEMBL7253210 | 0.67 | CYP19A1 (0.72) | MAPTHSD17B10KMT2AALDH1A1MEN1 | |
| SCHEMBL1677340 | 0.67 | MAPT (0.67) | MAPTHSD17B10KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284017-B1 | 4-(3-COUMARINYL)-THIAZOLE-DERIVATIVES WITH ANTI-ALLERGIC, ANTI-ANAPHYLACTIC AND ANTI-ARTHRITIC ACTIVITY AND COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.p.A. (IT) | 1991-09-11 | — | — | EP | disclosed |
| EP-0190298-B1 | 4-(ISOXAZOLYL)-THIAZOLE-2-OXAMIC ACIDS AND DERIVATIVES THEREOF | ZAMBON S.p.A. (IT) | 1989-10-18 | — | — | EP | disclosed |
| US-4829077-A | Benzopyran[4,3-d]-thiazole-derivatives with anti-allergic, anti-anaphylactic and anti-arithritic activity and compositions containing them | ZAMBON GROUP S.P.A. (IT) | 1989-05-09 | — | — | US | disclosed |
| EP-0284018-A2 | Benzopyran[4,3-d]-thiazole-derivatives with anti-allergic, anti-anaphylactic and anti-arthritic activity and compositions containing them | ZAMBON GROUP S.p.A. (IT) | 1988-09-28 | — | — | EP | disclosed |
| EP-0284017-A1 | 4-(3-coumarinyl)-thiazole-derivatives with anti-allergic, anti-anaphylactic and anti-arthritic activity and compositions containing them | ZAMBON GROUP S.p.A. (IT) | 1988-09-28 | — | — | EP | disclosed |
| US-4766137-A | 4-(isoxazolyl)-thiazole-2-oxamic acids and derivatives thereof | ZAMBON S.P.A. (IT) | 1988-08-23 | — | — | US | disclosed |
| EP-0190298-A1 | 4-(ISOXAZOLYL)-THIAZOLE-2-OXAMIC ACIDS AND DERIVATIVES THEREOF. | ZAMBON SPA (IT) | 1986-08-13 | — | — | EP | disclosed |
| WO-1986000900-A1 | 4-(ISOXAZOLYL)-THIAZOLE-2-OXAMIC ACIDS AND DERIVATIVES THEREOF | ZAMBON, S.P.A. (IT) | 1986-02-13 | — | — | WO | disclosed |