Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.54 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.54 |
| ▸ | ITGAL | P20701 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.48 |
| ▸ | TRHR | P34981 | 1/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | PPM1B | O75688 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828553 | 0.99 | EPHX2 (0.59) | EPHX2ITGB2ICAM1ITGALCA1 | |
| SCHEMBL29792521 | 0.83 | EPHX2 (0.51) | EPHX2ITGB2ICAM1ITGALCA1 | |
| SCHEMBL31339185 | 0.83 | EPHX2 (0.51) | EPHX2ITGB2ICAM1ITGALCA1 | |
| SCHEMBL31339177 | 0.83 | EPHX2 (0.51) | EPHX2ITGB2ICAM1ITGALCA1 | |
| SCHEMBL27777019 | 0.83 | EPHX2 (0.60) | EPHX2ITGB2ICAM1ITGALCA1 | |
| SCHEMBL27756048 | 0.82 | EPHX2 (0.62) | EPHX2ITGB2ICAM1ITGALCA1 | |
| SCHEMBL27413426 | 0.81 | ITGB2 (0.67) | EPHX2ITGB2ICAM1ITGALCA1 | |
| SCHEMBL27776878 | 0.80 | EPHX2 (0.52) | EPHX2ITGB2ICAM1ITGALCA1 | |
| SCHEMBL6026427 | 0.78 | ITGB2 (0.64) | EPHX2ITGB2ICAM1ITGALCA1 | |
| SCHEMBL5494124 | 0.78 | ITGB2 (0.61) | EPHX2ITGB2ICAM1ITGALCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |