Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.50 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.50 |
| ▸ | ITGAL | P20701 | 3/20 | 0.50 |
| ▸ | TRHR | P34981 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | REN | P00797 | 2/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | CTSC | P53634 | 1/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29792521 | 1.00 | EPHX2 (0.51) | EPHX2ITGB2ICAM1ITGALTRHR | |
| SCHEMBL31339185 | 1.00 | EPHX2 (0.51) | EPHX2ITGB2ICAM1ITGALTRHR | |
| SCHEMBL9829697 | 0.83 | EPHX2 (0.57) | EPHX2ITGB2ICAM1ITGALTRHR | |
| SCHEMBL27639586 | 0.82 | TRHR (0.49) | TRHRRENCAPN1 | |
| SCHEMBL27448784 | 0.82 | TRHR (0.49) | TRHRRENCAPN1 | |
| SCHEMBL9828553 | 0.82 | EPHX2 (0.59) | EPHX2ITGB2ICAM1ITGALTRHR | |
| SCHEMBL27504185 | 0.81 | TRHR (0.59) | TRHRRENCAPN1 | |
| SCHEMBL27273945 | 0.78 | CYP3A4 (0.50) | RENCYP3A4SLC7A5 | |
| SCHEMBL21219550 | 0.77 | TRHR (0.43) | TRHRRENCAPN1 | |
| SCHEMBL21219553 | 0.77 | REN (0.42) | TRHRRENCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4516282-A1 | NOVEL USES OF IMIDAZOLYL DERIVATIVES | Exsymol (MC) | 2025-03-05 | — | — | EP | disclosed |
| CN-119424238-A | New use of imidazolyl derivatives | 爱西美有限公司 | 2025-02-14 | — | — | CN | disclosed |