Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.51 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.51 |
| ▸ | ITGAL | P20701 | 3/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | PPM1B | O75688 | 2/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.47 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.46 |
| ▸ | GGT1 | P19440 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27756048 | 0.99 | EPHX2 (0.62) | EPHX2CYP3A4SLC7A5ITGB2ICAM1 | |
| SCHEMBL27756059 | 0.84 | HRH3 (0.51) | EPHX2EPHX1HRH3HRH4 | |
| SCHEMBL27776878 | 0.83 | EPHX2 (0.52) | EPHX2CYP3A4SLC7A5ITGB2ICAM1 | |
| SCHEMBL9829697 | 0.83 | EPHX2 (0.57) | EPHX2CYP3A4SLC7A5ITGB2ICAM1 | |
| SCHEMBL9828553 | 0.82 | EPHX2 (0.59) | EPHX2CYP3A4SLC7A5ITGB2ICAM1 | |
| SCHEMBL8257707 | 0.81 | CPB2 (0.55) | EPHX2CYP3A4SLC7A5ITGB2ICAM1 | |
| SCHEMBL3378643 | 0.79 | CYP3A4 (0.61) | EPHX2CYP3A4SLC7A5ITGB2ICAM1 | |
| SCHEMBL5833201 | 0.78 | ITGB2 (0.57) | EPHX2CYP3A4SLC7A5ITGB2ICAM1 | |
| SCHEMBL29938832 | 0.78 | ITGB2 (0.60) | EPHX2CYP3A4SLC7A5ITGB2ICAM1 | |
| SCHEMBL151336 | 0.78 | ITGB2 (0.60) | CYP3A4SLC7A5ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101531637-A | A novel compound capable of restraining and blocking M2 ion channel activity and application thereof | CHINESE ACADEMY OF SCIENCES GU | 2009-09-16 | — | — | CN | claimed |
| CN-101531637-B | A novel compound capable of restraining and blocking M2 ion channel activity and application thereof | CHINESE ACADEMY OF SCIENCES GUANGZHOU INST OF BIOMEDICINE AND HEALTH | 2011-07-13 | — | — | CN | disclosed |
| CN-101531637-A | A novel compound capable of restraining and blocking M2 ion channel activity and application thereof | CHINESE ACADEMY OF SCIENCES GU | 2009-09-16 | — | — | CN | disclosed |