Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 1/20 | 0.60 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.60 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.60 |
| ▸ | ITGAL | P20701 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | ECE1 | P42892 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16673595 | 0.84 | AGTR2 (0.58) | AGTR2ITGB2ICAM1ITGALCA1 | |
| SCHEMBL8250332 | 0.83 | AGTR2 (0.61) | AGTR2ITGB2ICAM1ITGALMEN1 | |
| SCHEMBL5869520 | 0.83 | AGTR2 (0.61) | AGTR2ITGB2ICAM1ITGALMEN1 | |
| SCHEMBL28042757 | 0.83 | SLC15A2 (0.70) | AGTR2ITGB2ICAM1ITGALS1PR1 | |
| SCHEMBL5907039 | 0.82 | AGTR2 (0.57) | AGTR2ITGB2ICAM1ITGALCA1 | |
| SCHEMBL3599440 | 0.82 | AGTR2 (0.57) | AGTR2ITGB2ICAM1ITGALCA1 | |
| Carnosine SCHEMBL22392772 | 0.82 | SLC15A2 (0.63) | AGTR2ITGB2ICAM1ITGALCA1 | |
| Carnosine SCHEMBL1160796 | 0.82 | SLC15A2 (0.63) | AGTR2ITGB2ICAM1ITGALCA1 | |
| SCHEMBL4525493 | 0.82 | CA1 (0.72) | AGTR2ITGB2ICAM1ITGALCA1 | |
| Carnosine SCHEMBL1161102 | 0.82 | SLC15A2 (0.63) | AGTR2ITGB2ICAM1ITGALCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240290431-A1 | BIOMARKER AND DIAGNOSIS SYSTEM FOR COLORECTAL CANCER DETECTION | HANGZHOU CALIBRA DIAGNOSTICS CO LTD (CN) | 2024-08-29 | — | — | US | claimed |
| CN-115440375-A | Colorectal cancer prediction system and application thereof | 杭州凯莱谱精准医疗检测技术有限公司 | 2022-12-06 | — | — | CN | claimed |
| CN-115436633-A | Biomarker for colorectal cancer detection and application thereof | 杭州凯莱谱精准医疗检测技术有限公司 | 2022-12-06 | — | — | CN | claimed |
| CN-114758719-A | Colorectal cancer prediction system and application thereof | 杭州凯莱谱精准医疗检测技术有限公司 | 2022-07-15 | — | — | CN | claimed |
| CN-114755422-A | Biomarker for colorectal cancer detection and application thereof | 杭州凯莱谱精准医疗检测技术有限公司 | 2022-07-15 | — | — | CN | claimed |
| US-20240290431-A1 | BIOMARKER AND DIAGNOSIS SYSTEM FOR COLORECTAL CANCER DETECTION | HANGZHOU CALIBRA DIAGNOSTICS CO LTD (CN) | 2024-08-29 | — | — | US | disclosed |
| US-20230402131-A1 | BIOMARKER AND DIAGNOSIS SYSTEM FOR COLORECTAL CANCER DETECTION | HANGZHOU CALIBRA DIAGNOSTICS CO., LTD. (CN) | 2023-12-14 | — | — | US | disclosed |
| CN-115440375-A | Colorectal cancer prediction system and application thereof | 杭州凯莱谱精准医疗检测技术有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-115436633-A | Biomarker for colorectal cancer detection and application thereof | 杭州凯莱谱精准医疗检测技术有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-114758719-B | Colorectal cancer prediction system and application thereof | 杭州凯莱谱精准医疗检测技术有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-114755422-B | Biomarker for colorectal cancer detection and application thereof | 杭州凯莱谱精准医疗检测技术有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-114758719-A | Colorectal cancer prediction system and application thereof | 杭州凯莱谱精准医疗检测技术有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114755422-A | Biomarker for colorectal cancer detection and application thereof | 杭州凯莱谱精准医疗检测技术有限公司 | 2022-07-15 | — | — | CN | disclosed |
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |