Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 1/20 | 0.57 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.56 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.56 |
| ▸ | ITGAL | P20701 | 3/20 | 0.56 |
| ▸ | GGT1 | P19440 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CPA1 | P15085 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | REN | P00797 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5907039 | 1.00 | AGTR2 (0.57) | AGTR2ITGB2ICAM1ITGALGGT1 | |
| SCHEMBL2059180 | 0.87 | SIRT2 (0.52) | AGTR2ITGB2ICAM1ITGALTAAR1 | |
| SCHEMBL1667212 | 0.87 | ALDH1A1 (0.54) | ITGB2ICAM1ITGALTAAR1CYP3A4 | |
| SCHEMBL8250332 | 0.85 | AGTR2 (0.61) | AGTR2ITGB2ICAM1ITGALTAAR1 | |
| SCHEMBL5869520 | 0.85 | AGTR2 (0.61) | AGTR2ITGB2ICAM1ITGALTAAR1 | |
| SCHEMBL6239445 | 0.85 | ITGB2 (0.52) | AGTR2ITGB2ICAM1ITGALGGT1 | |
| SCHEMBL9554563 | 0.84 | GGT1 (0.55) | AGTR2ITGB2ICAM1ITGALGGT1 | |
| SCHEMBL9829801 | 0.82 | AGTR2 (0.60) | AGTR2ITGB2ICAM1ITGALHIF1A | |
| SCHEMBL11208664 | 0.81 | ITGB2 (0.58) | AGTR2ITGB2ICAM1ITGALTAAR1 | |
| SCHEMBL7383006 | 0.81 | ITGB2 (0.53) | AGTR2ITGB2ICAM1ITGALGGT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7649001-B2 | Fused benzene derivative and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-01-19 | — | — | US | disclosed |
| US-20060217316-A1 | Method for the treatment of prostate cancer | GENIX THERAPEUTICS, INC. | 2006-09-28 | — | — | US | disclosed |
| US-20060106067-A1 | Fused benzene derivative and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-05-18 | — | — | US | disclosed |
| WO-2004087190-A1 | METHOD FOR THE TREATMENT OF PROSTATE CANCER | GENIX THERAPEUTICS INC. (US) | 2004-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106067-A1 | Fused benzene derivative and use | AR, NR5A1, CBR3 | AGTR2 104/4885ITGB2 1213/4885ICAM1 4017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.