Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 8/20 | 0.46 |
| ▸ | FNTB | P49356 | 8/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829817 | 1.00 | FNTA (0.46) | FNTAFNTBMETAP2METAP1ALDH1A1 | |
| SCHEMBL4957200 | 0.86 | ALDH1A1 (0.49) | METAP2METAP1ALDH1A1NPSR1LMNA | |
| SCHEMBL4957204 | 0.86 | ALDH1A1 (0.49) | METAP2METAP1ALDH1A1NPSR1LMNA | |
| Hydrochloric Acid SCHEMBL27865037 | 0.84 | ALDH1A1 (0.48) | METAP2METAP1ALDH1A1NPSR1LMNA | |
| Water SCHEMBL27588204 | 0.84 | ALDH1A1 (0.48) | METAP2METAP1ALDH1A1NPSR1LMNA | |
| SCHEMBL10754006 | 0.82 | FNTA (0.56) | FNTAFNTB | |
| SCHEMBL9830412 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNA | |
| SCHEMBL9830409 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNA | |
| SCHEMBL12479817 | 0.81 | FOLH1 (0.51) | METAP2METAP1ALDH1A1BACE1LMNA | |
| SCHEMBL30051883 | 0.80 | FNTA (0.53) | FNTAFNTBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |