Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.43 |
| ▸ | LAP3 | P28838 | 3/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830412 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MEN1LMNAKMT2AMME | |
| SCHEMBL9830039 | 0.86 | ALDH1A1 (0.58) | ALDH1A1MEN1LMNAKMT2AMME | |
| SCHEMBL729840 | 0.86 | ALDH1A1 (0.58) | ALDH1A1MEN1LMNAKMT2AMME | |
| SCHEMBL9557207 | 0.86 | ALDH1A1 (0.58) | ALDH1A1MEN1LMNAKMT2AMME | |
| SCHEMBL19787736 | 0.81 | MME (0.44) | ALDH1A1LMNAMMECTSKECE1 | |
| SCHEMBL31207145 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MEN1LMNAKMT2AMME | |
| SCHEMBL5663757 | 0.81 | CTSS (0.58) | ALDH1A1CTSBCTSK | |
| SCHEMBL9829817 | 0.81 | FNTA (0.46) | ALDH1A1LMNA | |
| SCHEMBL9829809 | 0.81 | FNTA (0.46) | ALDH1A1LMNA | |
| SCHEMBL25251125 | 0.80 | CTSK (0.65) | MMECTSBCTSKECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |