Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 6/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 11/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL981132 | 1.00 | KCNA5 (0.38) | KCNA5BRD4IRAK4PDK2 | |
| SCHEMBL981131 | 1.00 | KCNA5 (0.38) | KCNA5BRD4IRAK4PDK2 | |
| SCHEMBL16030453 | 0.90 | IRAK4 (0.36) | KCNA5BRD4IRAK4 | |
| Tert-Butyl Formate SCHEMBL27984964 | 0.86 | IRAK4 (0.35) | KCNA5BRD4IRAK4PDK2 | |
| Tert-Butyl Formate SCHEMBL27984962 | 0.86 | IRAK4 (0.35) | KCNA5BRD4IRAK4PDK2 | |
| SCHEMBL28460243 | 0.82 | CA2 (0.38) | KCNA5IRAK4PDK2 | |
| SCHEMBL10666154 | 0.79 | ITGB1 (0.39) | BRD4 | |
| SCHEMBL11062632 | 0.79 | ITGB1 (0.39) | BRD4 | |
| SCHEMBL14285551 | 0.77 | — | — | |
| SCHEMBL12409742 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110015200-A1 | NITROGEN-CONTAINING BYCYCLIC COMPOUNDS ACTIVE ON CHRONIC PAIN CONDITIONS | NEUROTUNE AG (CH) | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015200-A1 | NITROGEN-CONTAINING BYCYCLIC COMPOUNDS ACTIVE ON CHRONIC PAIN CONDITIONS | OPRL1, CNR1, OPRK1 | KCNA5 335/4885BRD4 2532/4885IRAK4 3272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.