Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | REN | P00797 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13256269 | 0.79 | HDAC4 (0.45) | CTSSCTSKHDAC4HDAC1HDAC6 | |
| SCHEMBL13256278 | 0.79 | HDAC4 (0.45) | CTSSCTSKHDAC4HDAC1HDAC6 | |
| SCHEMBL13256297 | 0.77 | HDAC4 (0.43) | CTSSCTSKHDAC4HDAC1HDAC6 | |
| SCHEMBL4753064 | 0.76 | GAA (0.47) | CTSSCTSKHDAC4HDAC1HDAC6 | |
| SCHEMBL13636231 | 0.76 | GAA (0.47) | CTSSCTSKHDAC4HDAC1HDAC6 | |
| SCHEMBL7264782 | 0.76 | GAA (0.47) | CTSSCTSKHDAC4HDAC1HDAC6 | |
| SCHEMBL7448540 | 0.75 | CTSS (0.42) | CTSSCTSKHDAC4HDAC1HDAC6 | |
| SCHEMBL4295798 | 0.75 | CTSK (0.44) | CTSSCTSKHDAC4HDAC1HDAC6 | |
| SCHEMBL10660697 | 0.75 | CTSK (0.44) | CTSSCTSKHDAC4HDAC1HDAC6 | |
| SCHEMBL16469899 | 0.75 | CTSK (0.44) | CTSSCTSKHDAC4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258289-A4 | PEPTIDE ANALOGS | — | 1991-01-02 | — | — | EP | disclosed |
| US-4826958-A | HYPOTENSIVE AGENTS | ABBOTT LABORATORIES (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0258289-A1 | PEPTIDE ANALOGS | ABBOTT LABORATORIES (US) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987004349-A1 | PEPTIDE ANALOGS | DELLARIA JOSEPH | 1987-07-30 | — | — | WO | disclosed |