Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.73 |
| ▸ | MEN1 | O00255 | 6/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.52 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.52 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31675013 | 0.87 | LMNA (0.80) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL29493744 | 0.84 | MEN1 (0.67) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL4733997 | 0.80 | KMT2A (1.00) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL9832525 | 0.79 | MEN1 (0.62) | KMT2AMEN1HTTLMNAL3MBTL1 | |
| SCHEMBL18600723 | 0.78 | SMN1; SMN2 (0.71) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL6510957 | 0.78 | SMN1; SMN2 (0.64) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL7753940 | 0.78 | KMT2A (0.59) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL26098679 | 0.77 | MAPT (0.65) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL29349665 | 0.76 | LMNA (0.59) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL2243374 | 0.76 | MAPT (0.72) | KMT2AMEN1MAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283035-B1 | BENZOXAZOLE DERIVATIVES AND PREPARATION THEREOF | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-06 | — | — | EP | disclosed |
| US-4948900-A | INTERMEDIATES FOR DIABETES THERAPEUTIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1990-08-14 | — | — | US | disclosed |
| US-4897393-A | ANTIDIABETIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| EP-0283035-A1 | Benzoxazole derivatives and preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |