Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6546363 | 0.92 | LMNA (0.64) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7754088 | 0.90 | KMT2A (0.58) | KMT2AALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL6546924 | 0.89 | KMT2A (0.57) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL6545821 | 0.89 | L3MBTL1 (0.68) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7749311 | 0.86 | KMT2A (0.54) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL11883066 | 0.84 | ALDH1A1 (0.63) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL7753274 | 0.82 | SMN1; SMN2 (0.55) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL31541287 | 0.82 | MEN1 (0.52) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL11157919 | 0.82 | MEN1 (0.52) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL7754151 | 0.81 | LMNA (0.66) | KMT2AMEN1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068176-A1 | CYSTEINE AMIDES AS FARNESYL TRANSFERASE INHIBITORS | Jomaa, Hassan (DE) | 2001-01-17 | — | — | EP | disclosed |
| WO-2000027803-A1 | CYSTEINE AMIDES AS FARNESYL TRANSFERASE INHIBITORS | JOMAA, HASSAN (DE) | 2000-05-18 | — | — | WO | disclosed |