Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ATP4A | P20648 | 1/20 | 0.49 |
| ▸ | ATP4B | P51164 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831109 | 0.83 | CYP1A1 (0.67) | ALDH1A1MAPTTDP1KDM4ELMNA | |
| SCHEMBL1180783 | 0.83 | CYP19A1 (0.76) | ALDH1A1MAPTTDP1KDM4ELMNA | |
| SCHEMBL1179709 | 0.81 | ALDH1A1 (0.63) | ALDH1A1MAPTTDP1KDM4ELMNA | |
| SCHEMBL9830040 | 0.80 | CDC25A (0.61) | ALDH1A1MAPTTDP1KDM4ECYP19A1 | |
| SCHEMBL23367891 | 0.79 | ALDH1A1 (0.60) | ALDH1A1MAPTTDP1KDM4ELMNA | |
| SCHEMBL19002554 | 0.79 | MAPT (0.75) | ALDH1A1MAPTTDP1KDM4ELMNA | |
| SCHEMBL1181045 | 0.79 | CYP19A1 (0.67) | ALDH1A1MAPTTDP1KDM4ELMNA | |
| SCHEMBL3508223 | 0.79 | ALDH1A1 (0.60) | ALDH1A1MAPTTDP1KDM4ELMNA | |
| SCHEMBL9832131 | 0.79 | MEN1 (0.54) | ALDH1A1MAPTSREBF2RAB9AATP4A | |
| SCHEMBL29462058 | 0.78 | MAPT (0.73) | ALDH1A1MAPTTDP1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |