Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CTH | P32929 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL679892 | 0.65 | KMO (0.37) | ALDH1A1TSHR | |
| SCHEMBL9728320 | 0.65 | — | — | |
| SCHEMBL8911520 | 0.65 | NPC1 (0.50) | ALDH1A1 | |
| SCHEMBL10866549 | 0.63 | — | — | |
| SCHEMBL17760501 | 0.61 | SCN9A (0.37) | TSHR | |
| SCHEMBL8910489 | 0.57 | CYP2C19 (0.40) | ALDH1A1 | |
| SCHEMBL217659 | 0.56 | POLB (0.44) | — | |
| SCHEMBL1119454 | 0.56 | POLB (0.44) | — | |
| SCHEMBL1119493 | 0.56 | POLB (0.44) | — | |
| SCHEMBL22588272 | 0.55 | PDGFRB (0.38) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0439556-A4 | HETEROCYCLIC PEPTIDE RENIN INHIBITORS | — | 1991-10-30 | — | — | EP | disclosed |