SCHEMBL217659

SCHEMBL217659

[CH](c1ccccc1)C1CCCCC1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.44
GAA P10253 1/20 0.44
G6PC1 P35575 1/20 0.42
HSP90AA1 P07900 2/20 0.41
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
KDM4E B2RXH2 1/20 0.41
MAOB P27338 1/20 0.40
IDO1 P14902 2/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
THRB P10828 1/20 0.38
TRPM8 Q7Z2W7 1/20 0.38
GRIN1 Q05586 1/20 0.38
GRIN2B Q13224 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1119454 1.00 POLB (0.44) POLBGAAG6PC1HSP90AA1MAPK1
SCHEMBL1119493 1.00 POLB (0.44) POLBGAAG6PC1HSP90AA1MAPK1
SCHEMBL316481 0.98 POLB (0.45) POLBGAAG6PC1HSP90AA1MAPK1
SCHEMBL1119433 0.93 ALDH1A1 (0.42) POLBGAASMN1; SMN2KDM4EMAOB
SCHEMBL674275 0.87 MAOB (0.46) POLBGAASMN1; SMN2MAOBMAPT
SCHEMBL164340 0.77 MAOA (0.51) MAOB
SCHEMBL933856 0.77 MAOA (0.51) MAOB
SCHEMBL8910489 0.77 CYP2C19 (0.40) POLBHSP90AA1MAPK1SMN1; SMN2KDM4E
SCHEMBL6002937 0.77 SLC18A3 (0.48) MAOB
SCHEMBL7055107 0.77 TRPM8 (0.44) POLBSMN1; SMN2MAOBMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 460 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4382546-A1 POLY(UREA-URETHANE) POLYMER BASF SE (DE) 2024-06-12 EP claimed
WO-2024105029-A1 RECYCLABLE POLY(UREA-URETHANE) POLYMER AND COMPOSITE WITH DYNAMIC HINDERED UREA BONDS (HUBS) BASF SE (DE) 2024-05-23 WO claimed
EP-1592738-B1 RESIN COMPOSITIONS CIBA HOLDING INC (CH) 2020-07-29 EP claimed
EP-3277649-B1 TRANSALKYLATED CYCLOHEXYLBENZYL AND BIPHENYL COMPOUNDS EXXONMOBIL CHEMICAL PATENTS INC (US) 2019-08-21 EP claimed
US-10017433-B2 Transalkylated cyclohexylbenzyl and biphenyl compounds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-07-10 US claimed
US-20180050971-A1 Transalkylated Cyclohexylbenzyl and Biphenyl Compounds EXXONMOBIL CHEMICAL PATENTS INC. 2018-02-22 US claimed
EP-3277649-A1 TRANSALKYLATED CYCLOHEXYLBENZYL AND BIPHENYL COMPOUNDS ExxonMobil Chemical Patents Inc. (US) 2018-02-07 EP claimed
CN-107438590-A The cyclohexyl benzyl and biphenol compound of transfering alkylation 埃克森美孚化学专利公司 2017-12-05 CN claimed
CN-106432571-A Polymer composition and process for making the same 爱伦环球有限公司 2017-02-22 CN claimed
US-20170030015-A1 POLYMER COMPOSITION AND PROCESS FOR MAKING THE SAME ARON UNIVERSAL LTD. (IN) 2017-02-02 US claimed
US-5639775-A COGNITION ACTIVATORS THE UNIVERSITY OF TOLEDO (US) 1997-06-17 US claimed
US-5633382-A Histamine H3 -receptor antagonists and therapeutic uses thereof THE UNIVERSITY OF TOLEDO (US) 1997-05-27 US claimed
EP-0480659-B1 Use of Angiotensin-II antagonists for the manufacture of a medicament for the treatment of hyperuricemia MERCK & CO INC (US) 1996-09-04 EP claimed
EP-0633882-A1 4- 4'-PIPERIDINYL OR 3'-PIRROLIDINYL] SUBSTITUTED IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS AND THERAPEUTIC USES THEREOF THE UNIVERSITY OF TOLEDO (US) 1995-01-18 EP claimed
EP-0242618-B1 Transparent optical article and process for preparing same NIPPON OILS & FATS CO LTD (JP) 1994-11-02 EP claimed
US-5260322-A Angiotension II antagonists in the treatment of hyperuricemia MERCK & CO., INC. (US) 1993-11-09 US claimed
WO-1993020061-A1 4-[4'-PIPERIDINYL OR 3'-PIRROLIDINYL] SUBSTITUTED IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS AND THERAPEUTIC USES THEREOF THE UNIVERSITY OF TOLEDO (US) 1993-10-14 WO claimed
EP-0480659-A2 Use of Angiotensin-II antagonists for the manufacture of a medicament for the treatment of hyperuricemia MERCK & CO. INC. (US) 1992-04-15 EP claimed
EP-0242618-A2 Transparent optical article and process for preparing same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1987-10-28 EP claimed
US-3971804-A ACARICIDES, FUNGICIDES, INSECTICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10017433-B2 Transalkylated cyclohexylbenzyl and biphenyl compounds DDT, CYP2B6, AHR POLB 430/4885GAA 1725/4885G6PC1 4721/4885
US-20180050971-A1 Transalkylated Cyclohexylbenzyl and Biphenyl Compounds DDT, CYP2B6, AHR POLB 430/4885GAA 1725/4885G6PC1 4721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.