Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.70 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.58 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830734 | 0.98 | CASP2 (0.74) | CASP2EPHX2ADRA1APLA2G2APRMT1 | |
| SCHEMBL9262199 | 0.98 | CASP2 (0.74) | CASP2EPHX2ADRA1APLA2G2APRMT1 | |
| SCHEMBL1289417 | 0.98 | CASP2 (0.74) | CASP2EPHX2ADRA1APLA2G2APRMT1 | |
| Myristic Acid SCHEMBL20893594 | 0.94 | CASP2 (0.81) | CASP2EPHX2PLA2G2AKDM4ENAAA | |
| SCHEMBL7749788 | 0.94 | CASP2 (0.67) | CASP2EPHX2ADRA1APLA2G2APRMT1 | |
| SCHEMBL9829191 | 0.90 | EPHX2 (0.73) | CASP2EPHX2ADRA1APLA2G2AKDM4E | |
| SCHEMBL9830121 | 0.90 | EPHX2 (0.78) | CASP2EPHX2PLA2G2AKDM4ENAAA | |
| SCHEMBL7537764 | 0.89 | CASP2 (0.86) | CASP2EPHX2NAAAMEN1KMT2A | |
| SCHEMBL23052005 | 0.88 | EPHX2 (0.81) | CASP2EPHX2PLA2G2AKDM4ENAAA | |
| SCHEMBL22072061 | 0.88 | EPHX2 (0.81) | CASP2EPHX2PLA2G2AKDM4ENAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220395589-A1 | POLYMERIC NANOPARTICLES FOR INTRACELLULAR PROTEIN DELIVERY | THE JOHNS HOPKINS UNIVERSTY | 2022-12-15 | — | — | US | disclosed |
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220395589-A1 | POLYMERIC NANOPARTICLES FOR INTRACELLULAR PROTEIN DELIVERY | LNPEP, EEA1, CLTB | CASP2 3600/4885EPHX2 4616/4885ADRA1A 3976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.