Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 13/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830637 | 0.86 | HSD11B1 (0.54) | HSD11B1NR1H3NR1H2 | |
| SCHEMBL9830092 | 0.85 | HSD11B1 (0.51) | HSD11B1PTGES | |
| SCHEMBL9829646 | 0.85 | HSD11B1 (0.47) | HSD11B1NR1H3NR1H2 | |
| SCHEMBL9829810 | 0.83 | HSD11B1 (0.54) | HSD11B1NR1H3NR1H2P2RX7 | |
| SCHEMBL9830832 | 0.82 | HSD11B1 (0.44) | HSD11B1NR1H3NR1H2KDM4E | |
| SCHEMBL9830317 | 0.77 | HSD11B1 (0.55) | HSD11B1 | |
| SCHEMBL9830794 | 0.76 | HSD11B1 (0.53) | HSD11B1P2RX7 | |
| SCHEMBL9275319 | 0.76 | HSD11B1 (0.54) | HSD11B1 | |
| SCHEMBL9832092 | 0.74 | HSD11B1 (0.52) | HSD11B1 | |
| SCHEMBL9831536 | 0.74 | HSD11B1 (0.55) | HSD11B1NR1H3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185256-B1 | TRIAZOLE DERIVATES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | CIBA-GEIGY AG (CH) | 1991-01-30 | — | — | EP | claimed |