Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 8/20 | 0.38 |
| ▸ | TPSD1 | Q9BZJ3 | 8/20 | 0.38 |
| ▸ | TPSG1 | Q9NRR2 | 8/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 4/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.33 |
| ▸ | PLG | P00747 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
| ▸ | CPN1 | P15169 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831197 | 0.89 | ATM (0.40) | TPSAB1TPSD1TPSG1ATMF2 | |
| SCHEMBL28521242 | 0.80 | ATM (0.42) | TPSAB1TPSD1TPSG1ATMF2 | |
| SCHEMBL9829905 | 0.80 | TPSAB1 (0.38) | TPSAB1TPSD1TPSG1ATMF2 | |
| SCHEMBL29107128 | 0.78 | TEAD1 (0.41) | TPSAB1TPSD1TPSG1ATM | |
| SCHEMBL7295825 | 0.77 | ATM (0.44) | ATMGAA | |
| Hydrochloric Acid SCHEMBL9835606 | 0.76 | CPN1 (0.39) | TPSAB1TPSD1TPSG1ATMF2 | |
| Hydrochloric Acid SCHEMBL9833904 | 0.76 | TPSAB1 (0.38) | TPSAB1TPSD1TPSG1ATMF2 | |
| SCHEMBL28669901 | 0.76 | HPGD (0.50) | ATM | |
| SCHEMBL28883716 | 0.74 | ATM (0.42) | TPSAB1TPSD1TPSG1ATMGAA | |
| SCHEMBL29144075 | 0.74 | TPSAB1 (0.44) | TPSAB1TPSD1TPSG1ATMF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | claimed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | claimed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | claimed |
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |