Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 10/20 | 0.38 |
| ▸ | TPSD1 | Q9BZJ3 | 10/20 | 0.38 |
| ▸ | TPSG1 | Q9NRR2 | 10/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.35 |
| ▸ | F2 | P00734 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CPN1 | P15169 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 3/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831197 | 0.90 | ATM (0.40) | TPSAB1TPSD1TPSG1ATMPRSS1 | |
| SCHEMBL28523191 | 0.83 | ATM (0.42) | TPSAB1TPSD1TPSG1ATMSMN1; SMN2 | |
| SCHEMBL28999414 | 0.80 | ATM (0.43) | ATMSMN1; SMN2 | |
| SCHEMBL9830416 | 0.80 | TPSAB1 (0.38) | TPSAB1TPSD1TPSG1ATMPRSS1 | |
| SCHEMBL20240601 | 0.79 | BTK (0.41) | — | |
| SCHEMBL28591188 | 0.79 | BTK (0.41) | — | |
| Hydrochloric Acid SCHEMBL9836420 | 0.79 | CPN1 (0.40) | TPSAB1TPSD1TPSG1ATMPRSS1 | |
| Hydrochloric Acid SCHEMBL9836413 | 0.79 | CPN1 (0.40) | TPSAB1TPSD1TPSG1ATMPRSS1 | |
| Hydrochloric Acid SCHEMBL9836812 | 0.79 | ALDH1A1 (0.38) | TPSAB1TPSD1TPSG1ATMPRSS1 | |
| SCHEMBL21634671 | 0.79 | HPGD (0.48) | ATMSMN1; SMN2CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | claimed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | claimed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | claimed |
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |