Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.61 |
| ▸ | CA1 | P00915 | 5/20 | 0.61 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.58 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.57 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | DHFR | P00374 | 2/20 | 0.51 |
| ▸ | GART | P22102 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL714972 | 1.00 | CA2 (0.61) | CA2CA1FOLH1TAS1R3TAS1R1 | |
| SCHEMBL27564186 | 0.88 | CA2 (0.75) | CA2CA1FOLH1CA12CA9 | |
| SCHEMBL9829563 | 0.84 | CA2 (0.63) | CA2CA1TAS1R3TAS1R1CA12 | |
| SCHEMBL9829566 | 0.84 | CA2 (0.63) | CA2CA1TAS1R3TAS1R1CA12 | |
| SCHEMBL8379946 | 0.84 | CA2 (0.66) | CA2CA1FOLH1CA12CA9 | |
| SCHEMBL1640055 | 0.84 | CA2 (0.66) | CA2CA1FOLH1CA12CA9 | |
| SCHEMBL10659527 | 0.83 | CA2 (0.54) | CA2CA1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL9831656 | 0.83 | CA2 (0.65) | CA2CA1FOLH1TAS1R3TAS1R1 | |
| SCHEMBL10659530 | 0.83 | CA2 (0.54) | CA2CA1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL9831665 | 0.83 | CA2 (0.65) | CA2CA1FOLH1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |