Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
| ▸ | EBPL | Q9BY08 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829526 | 0.90 | DRD2 (0.40) | SIGMAR1HTR1A | |
| SCHEMBL9831340 | 0.83 | EBP (0.45) | EBPSIGMAR1TMEM97ADRA1DADRA1A | |
| SCHEMBL9830031 | 0.81 | MAPT (0.37) | — | |
| Oxalic Acid SCHEMBL9829045 | 0.79 | TDP1 (0.48) | — | |
| Oxalic Acid SCHEMBL9829050 | 0.79 | TDP1 (0.48) | — | |
| SCHEMBL9829352 | 0.78 | SMPD1 (0.45) | ABCB1 | |
| Hydrochloric Acid SCHEMBL9828610 | 0.76 | SMPD1 (0.46) | ABCB1 | |
| Oxalic Acid SCHEMBL10672405 | 0.76 | KDM4E (0.48) | ADRA1AABCB1 | |
| SCHEMBL9830047 | 0.76 | SCN9A (0.34) | — | |
| SCHEMBL9830263 | 0.76 | MAPT (0.51) | ADRA1DADRA1AADRA1BHTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233291-B1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4739050-A | CALCIUM ANTAGONIST, ANTICOAGULANT | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |