Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 4/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9829050 | 1.00 | TDP1 (0.48) | TDP1ACHEBCHEMAOAMAOB | |
| SCHEMBL9829526 | 0.80 | DRD2 (0.40) | — | |
| SCHEMBL9830625 | 0.79 | EBP (0.48) | — | |
| Oxalic Acid SCHEMBL10672405 | 0.77 | KDM4E (0.48) | KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL9830031 | 0.74 | MAPT (0.37) | L3MBTL1KDM4EKMT2AALDH1A1 | |
| Oxalic Acid SCHEMBL9831201 | 0.73 | DRD2 (0.35) | KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL9830263 | 0.73 | MAPT (0.51) | TDP1ACHEKDM4EMEN1KMT2A | |
| SCHEMBL9830047 | 0.69 | SCN9A (0.34) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL9829460 | 0.69 | MAPT (0.38) | KDM4EMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9829644 | 0.68 | HRH1 (0.41) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233291-B1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4739050-A | CALCIUM ANTAGONIST, ANTICOAGULANT | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |