Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | CCR6 | P51684 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831599 | 0.91 | PKM (0.57) | PKMKDM4ETDP1ALOX12CYP3A4 | |
| SCHEMBL9829436 | 0.90 | PKM (0.61) | PKMKDM4ETDP1ALOX12CYP3A4 | |
| SCHEMBL29126819 | 0.89 | PKM (0.62) | PKMKDM4ETDP1ALOX12CYP3A4 | |
| SCHEMBL9065232 | 0.87 | PKM (0.60) | PKMKDM4ETDP1ALOX12CYP3A4 | |
| SCHEMBL342559 | 0.86 | PKM (0.67) | PKMKDM4ETDP1ALOX12CYP3A4 | |
| SCHEMBL29514385 | 0.86 | PKM (0.67) | PKMKDM4ETDP1ALOX12CYP3A4 | |
| SCHEMBL9831501 | 0.84 | ALDH1A1 (0.63) | PKMKDM4ETDP1ALOX12CYP3A4 | |
| SCHEMBL9245052 | 0.84 | PKM (0.62) | PKMKDM4ETDP1ALOX12CYP3A4 | |
| SCHEMBL9247516 | 0.83 | PKM (0.61) | PKMKDM4ETDP1ALOX12CYP3A4 | |
| SCHEMBL9134176 | 0.82 | PKM (0.66) | PKMKDM4ETDP1ALOX12CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0191736-B1 | USE OF QUINOLINE DERIVATIVES FOR THE PROTECTION OF CROP PLANTS | CIBA-GEIGY AG (CH) | 1991-07-17 | — | — | EP | claimed |
| US-4881966-A | PLANT SAFENING AGENTS | CIBA-GEIGY CORPORATION (US) | 1989-11-21 | — | — | US | disclosed |